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Invitrogen
UGCG Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-54986
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UGCG. Recombinant protein control fragment (Product #RP-93000).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RLHLNKKATD KQPYSKLPGV SLLKPLKGVD PNLINNLETF FELDYPKYEV LLCVQDHDDP AIDVCKKLLG KYPNVDARLF IGGKKVGINP KINNLMPGYE VAKYDLI
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
May serve as a "flippase" as well as a glucosyltransferase that transfers glucose to ceramide. It Catalyzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glucosylceramide synthase; glycosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; unnamed protein product
Gene Aliases: GCS; GLCT1
UniProt ID: (Human) Q16739
Entrez Gene ID: (Human) 7357
protein lipidation
sphingolipid metabolic process
glucosylceramide biosynthetic process
glycosphingolipid biosynthetic process
epidermis development
regulation of signal transduction
cell differentiation
keratinocyte differentiation
leptin-mediated signaling pathway
neuron development
establishment of skin barrier
intestinal lipid absorption
cornified envelope assembly
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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