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Invitrogen
CDCA7L Polyclonal Antibody
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Product Details
PA5-55533
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CDCA7L. Recombinant protein control fragment (Product #RP-88699).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VRFHSKYFTE ELRRIFIEDT DSETEDFAGF TQSDLNGKTN PEVMVVESDL SDDGKASLVS EEEEDEEEDK ATPRRSRSRR SSIGLRVAFQ FPTKKLANKP DKNSSSEQLF SSARLQNEKK TILERKKDCR QVIQREDSTS ESE
Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 57%.
Target Information
Cell division cycle-associated 7-like protein (or RAM2) is a transcription factor which plays a role in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell division cycle-associated 7-like protein; Protein JPO2; Transcription factor RAM2; unnamed protein product
Gene Aliases: CDCA7L; HR1; JPO2; R1; RAM2
UniProt ID: (Human) Q96GN5
Entrez Gene ID: (Human) 55536
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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