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Invitrogen
MOXD1 Polyclonal Antibody
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Product Details
PA5-57381
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MOXD1. Recombinant protein control fragment (Product #RP-95050).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DINDKSITDS TVRVIWAYHH EDAGEAGPKY HDSNRGTKSL RLLNPEKTSV LSTALPYFDL VNQDVPIPNK DTTYWCQMFK IPVFQEKHHV IKVEPV
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 90%.
Target Information
The MOXD1 (Monooxygenase, DBH-like 1) gene encodes a protein that is part of the copper type II, ascorbate-dependent monooxygenase family, which includes enzymes such as dopamine beta-hydroxylase. Located on chromosome 6, the MOXD1 protein plays a role in the biosynthesis of bioactive amines, though its specific substrate and biological functions are less well characterized compared to its family members. This enzyme's activity is implicated in various physiological processes, including the metabolism of neurotransmitters and regulation of blood pressure. Research has suggested that MOXD1 might be involved in oncogenesis, with altered expression observed in certain cancer types. Further studies are needed to elucidate its precise physiological roles and potential as a therapeutic target.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DBH-like monooxygenase protein 1; dopamine-oxygenase; Monooxygenase X; MOX; similar to dopamine beta-hydroxylase; unnamed protein product
Gene Aliases: dJ248E1.1; MOX; MOXD1; PRO5780; UNQ2493/PRO5780
UniProt ID: (Human) Q6UVY6
Entrez Gene ID: (Human) 26002
catalytic activity
monooxygenase activity
dopamine beta-monooxygenase activity
copper ion binding
protein binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
metal ion binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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