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Invitrogen
GPN1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-57822
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GPN1. Recombinant protein control fragment (Product #RP-96010).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LNQETTYVSN LTRSMSLVLD EFYSSLRVVG VSAVLGTGLD ELFVQVTSAA EEYEREYRPE YERLKKSLAN AESQQQREQL ERLRKDMGSV
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 89%.
Target Information
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GPN-loop GTPase 1; MBD2-interacting protein; MBDin; methyl-CpG binding domain protein 2 interacting protein; RNAPII-associated protein 4; XPA binding protein 1; XPA-binding protein 1
Gene Aliases: 2410004J02Rik; AI449615; GPN1; HUSSY-23; MBDIN; NTPBP; RPAP4; XAB1
UniProt ID: (Mouse) Q8VCE2
Entrez Gene ID: (Rat) 688393, (Mouse) 74254
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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