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Invitrogen
VPS51 Polyclonal Antibody
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Product Details
PA5-58869
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human VPS51. Recombinant protein control fragment (Product #RP-97383).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FDPEVYLDKL RRECPLAQLM DSETDMVRQI RALDSDMQTL VYENYNKFIS ATDTIRKMKN DFRKMEDEMD RLATNMAVIT DFS
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Another new gene 2 protein; Protein fat-free homolog; vacuolar protein sorting 51 homolog; Vacuolar protein sorting-associated protein 51 homolog; VPS51 GARP complex subunit
Gene Aliases: ANG2; ANG3; C11orf2; C11orf3; FFR; PP5382; VPS51
UniProt ID: (Human) Q9UID3
Entrez Gene ID: (Human) 738
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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