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Invitrogen
MKKS Polyclonal Antibody
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Product Details
PA5-60653
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MKKS. Recombinant protein control fragment (Product #RP-99409).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KSTALKVALF CTTLSGDTSD TGEGTVVVSY GVSLENAVLD QLLNLGRQLI SDHVDLVLCQ KVIHPSLKQF LNMHRIIAID RIGVTLMEPL TK
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 80%.
Target Information
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 6 protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Molecular chaperone MKKS
Gene Aliases: BBS6; HMCS; KMS; MKKS; MKS
UniProt ID: (Human) Q9NPJ1
Entrez Gene ID: (Human) 8195
heart looping
protein folding
spermatid development
determination of left/right symmetry
heart development
visual perception
sensory perception of smell
gonad development
negative regulation of gene expression
artery smooth muscle contraction
striatum development
hippocampus development
cerebral cortex development
negative regulation of actin filament polymerization
melanosome transport
negative regulation of GTPase activity
nonmotile primary cilium assembly
social behavior
negative regulation of appetite by leptin-mediated signaling pathway
positive regulation of multicellular organism growth
vasodilation
cilium assembly
fat cell differentiation
photoreceptor cell maintenance
negative regulation of blood pressure
intracellular transport
brain morphogenesis
detection of mechanical stimulus involved in sensory perception of sound
chaperone-mediated protein complex assembly
cartilage development
regulation of stress fiber assembly
pigment granule aggregation in cell center
convergent extension involved in gastrulation
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
face development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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