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Invitrogen
OAZ3 Polyclonal Antibody
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Product Details
PA5-65056
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human OAZ3. Recombinant protein control fragment (Product #RP-105822).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VNFQNDRNDRG ALLRAFSYMG FEVVRPDHPA LPPLDNVIFM VYPLERDVGH LPSEPP
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 77%.
Target Information
The antizyme family is a group of small proteins that play a role in cell growth and division by regulating the biosynthesis of polyamines such as putrescine, spermidine and spermine. AZ3, also known as OAZ3 (Ornithine decarboxylase antizyme 3), is a 187 amino acid protein that belongs to the ODC antizyme family. AZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells because it binds to, and destabilizes, ornithine decarboxylase. However, mutations in the AZ3 gene are not a common cause of male infertility and the normal AZ3 protein does not accelerate ornithine decarboxylase degeneration. AZ3 expression has a sharp onset in early spermatids, peaks in later stages and is gone in spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: antizyme 3; AZ3; ODC-Az 3; Ornithine decarboxylase antizyme 3; testicular secretory protein Li 31
Gene Aliases: AZ3; OAZ-t; OAZ3; TISP15
UniProt ID: (Human) Q9UMX2
Entrez Gene ID: (Human) 51686
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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