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Invitrogen
eIF2b gamma Polyclonal Antibody
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Product Details
PA5-82871
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EIF2B3. Recombinant protein control fragment (Product #RP-94012).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QRDFIGVDST GKRLLFMANE ADLDEELVIK GSILQKHPRI RFHTGLVDAH LYCLKKYIVD FLMENGSITS IRSELIPYLV RKQFSSASSQ QG
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 95%.
Target Information
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; Translation initiation factor eIF2B subunit gamma
Gene Aliases: EIF-2B; EIF2B3; EIF2Bgamma
UniProt ID: (Human) Q9NR50
Entrez Gene ID: (Human) 8891
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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