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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QRDFIGVDST GKRLLFMANE ADLDEELVIK GSILQKHPRI RFHTGLVDAH LYCLKKYIVD FLMENGSITS IRSELIPYLV RKQFSSASSQ QG
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 95%.
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF2B GDP-GTP exchange factor subunit gamma; Translation initiation factor eIF2B subunit gamma
Gene Aliases: EIF2B3
Entrez Gene ID: (Human) 8891
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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