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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: EALIHQLKIN PYVLSDKDRA NLINNIFELA GLGKVPLKRA FDLINYLGNE NHTAPITEAL FQTDLIYNLL EKLGYMDLAS RLVTRVFKLL QNQIQQQTWT DEGTPSMREL RSALLEFACT HNLGNCSTTA MKL
Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 87%.
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cystinyl aminopeptidase; Insulin-regulated membrane aminopeptidase; Insulin-responsive aminopeptidase; IRAP; Leucyl-cystinyl aminopeptidase; OTase; Oxytocinase; P-LAP; Placental leucine aminopeptidase; vp160
Gene Aliases: LNPEP; OTASE
Entrez Gene ID: (Human) 4012
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