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Invitrogen
LNPEP Polyclonal Antibody
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Product Details
PA5-83672
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LNPEP. Recombinant protein control fragment (Product #RP-90122).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EALIHQLKIN PYVLSDKDRA NLINNIFELA GLGKVPLKRA FDLINYLGNE NHTAPITEAL FQTDLIYNLL EKLGYMDLAS RLVTRVFKLL QNQIQQQTWT DEGTPSMREL RSALLEFACT HNLGNCSTTA MKL
Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 87%.
Target Information
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: angiotensin IV receptor; AT (4) receptor; Cystinyl aminopeptidase; insulin-regulated aminopeptidase; Insulin-regulated membrane aminopeptidase; Insulin-responsive aminopeptidase; IRAP; Leucyl-cystinyl aminopeptidase; OTase; Oxytocinase; P-LAP; Placental leucine aminopeptidase; unnamed protein product; vasopressinase; vp160
Gene Aliases: CAP; IRAP; LNPEP; OTASE; P-LAP; PLAP
UniProt ID: (Human) Q9UIQ6
Entrez Gene ID: (Human) 4012
protein polyubiquitination
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
proteolysis
cell-cell signaling
female pregnancy
regulation of blood pressure
neuropeptide catabolic process
protein catabolic process
negative regulation of cold-induced thermogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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