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Invitrogen
Carabin Polyclonal Antibody
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Product Details
PA5-84823
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TBC1D10C. Recombinant protein control fragment (Product #RP-104208).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DLVQPPELQD DSSSLGSDSE LSGPGPYRQA DRYGFIGGSS AEPGPGHPPA DLIRQREMKW VEM
Highest antigen sequence indentity to the following orthologs: Rat - 84%, Mouse - 76%.
Target Information
Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carabin; TBC1 domain family member 10C; TBC1 domain family, member 10C
Gene Aliases: CARABIN; EPI64C; TBC1D10C
UniProt ID: (Human) Q8IV04
Entrez Gene ID: (Human) 374403
intracellular protein transport
regulation of vesicle fusion
retrograde transport, endosome to Golgi
negative regulation of B cell activation
negative regulation of NFAT protein import into nucleus
negative regulation of ERK1 and ERK2 cascade
activation of GTPase activity
regulation of cilium assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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