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Invitrogen
PI4KA Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100301
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PI4KA(Accession P42356), corresponding to amino acid residues T1449-E1499.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PI4KA.
Target Information
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by PI4KA is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for PI4KA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leuserpin 2; phosphatidylinositol 4-kinase; phosphatidylinositol 4-kinase 230; phosphatidylinositol 4-kinase a; phosphatidylinositol 4-kinase III alpha; phosphatidylinositol 4-kinase IIII+/-; phosphatidylinositol 4-kinase, catalytic, alpha; phosphatidylinositol 4-kinase, catalytic, alpha polypeptide; phosphatidylinositol 4-kinase, type III, alpha; PI4-kinase alpha; PI4K230; ptdIns-4-kinase alpha; testicular secretory protein Li 35; unnamed protein product
Gene Aliases: GIDID2; PI4K-ALPHA; pi4K230; PIK4CA; PMGYCHA; SPG84
UniProt ID: (Human) P42356, (Mouse) E9Q3L2
Entrez Gene ID: (Human) 5297, (Rat) 64161, (Mouse) 224020
phosphatidylinositol biosynthetic process
signal transduction
myelination in peripheral nervous system
modulation by host of viral process
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
reorganization of cellular membranes to establish viral sites of replication
actin cytoskeleton organization
Schwann cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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