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Invitrogen
IL18R1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102647
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IL18R1(Accession Q13478), corresponding to amino acid residues V233-R283.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total IL18R1.
Target Information
IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD218 antigen-like family member A; cytokine receptor; IL-18R-1; IL-18R-alpha; IL-18R1; IL-18Ralpha; IL-1Rrp; IL1 receptor-related protein; IL18Ralpha2; IL1R-rp; interleukin 1 receptor related protein; Interleukin-18; interleukin-18 receptor alpha; unnamed protein product
Gene Aliases: CD218a; CDw218a; IL-18R; IL-18R-alpha; IL-18Ralpha; IL-1Rrp; IL18RA; Il18ralpha; IL18Ralpha2; IL1RRP
UniProt ID: (Human) Q13478, (Mouse) Q61098
Entrez Gene ID: (Human) 8809, (Rat) 301365, (Mouse) 16182
adaptive immune response
immune response
signal transduction
biological_process
natural killer cell activation
positive regulation of interferon-gamma production
interleukin-18-mediated signaling pathway
T-helper 1 cell differentiation
negative regulation of cold-induced thermogenesis
positive regulation of NIK/NF-kappaB signaling
positive regulation of T-helper 1 cell cytokine production
negative regulation of inflammatory response
defense response to Gram-positive bacterium
cellular response to lipopolysaccharide
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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