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Invitrogen
PRPS1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-105305
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PRPS1(Accession P60891), corresponding to amino acid residues K153-D203.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PRPS1.
Target Information
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deafness 2, perceptive, congenital; deafness, X-linked 2, perceptive, congenital; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); phosphoribosyl pyrophosphate synthase I; phosphoribosyl pyrophosphate synthetase I; phosphoribosylpyrophosphate synthetase (PRPS1) precursor; PRS-I; ribose-phosphate diphosphokinase 1; unnamed protein product
Gene Aliases: 2310010D17Rik; ARTS; CMTX5; DFN2; DFNX1; PPRibP; Prps-1; PRS-I; PRSI
UniProt ID: (Human) P60891, (Rat) P60892, (Mouse) Q9D7G0
Entrez Gene ID: (Human) 5631, (Rat) 29562, (Mouse) 19139
5-phosphoribose 1-diphosphate biosynthetic process
purine nucleobase metabolic process
purine nucleotide biosynthetic process
pyrimidine nucleotide biosynthetic process
nervous system development
male gonad development
ribonucleoside monophosphate biosynthetic process
nucleotide biosynthetic process
protein hexamerization
urate biosynthetic process
hypoxanthine biosynthetic process
pentose-phosphate shunt
AMP biosynthetic process
organ regeneration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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