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Invitrogen
ULK4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-110548
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human ULK4 (NP_060356.2).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Amount
33 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MENFILYEEI GRGSKTVVYK GRRKGTINFV AILCTDKCKR PEITNWVRLT REIKHKNIVT FHEWYETSNH LWLVVELCTG GSLKTVIAQD ENLPEDVVRE FGIDLISGLH HLHKLGILFC DISPRKILLE GPGTLKFSNF CLAKVEGENL EEFFALVAAE EGGGDNGENV LKKSMKSRVK GSPVYTAPEV VRGADFSISS DLWSLGCLLY EMFSGKPPFF SESISELTEK ILCEDPLPPI PKDSSRPKAS SDFINLLDGL LQRDPQKRLT WTRLLQHSFW KKAFAGADQE
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ULK4 (unc-51-like kinase 4) is a 1,275 amino acid protein that contains one protein kinase domain and one HEAT repeat and belongs to the Ser/Thr protein kinase family. Although containing what is thought to be a catalytically inactive domain, ULK4 may play a role in the ATP-dependent phosphorylation of target proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pseudokinase ULK4; serine/threonine-protein kinase ULK4; unnamed protein product
Gene Aliases: 4932415A06Rik; A730098P15; FAM7C1; REC01035; RGD1565726
UniProt ID: (Human) Q96C45, (Mouse) Q3V129
Entrez Gene ID: (Human) 54986, (Rat) 363167, (Mouse) 209012
microtubule cytoskeleton organization
epithelial cilium movement
smoothened signaling pathway
brain development
sensory perception
learning or memory
memory
adult walking behavior
biological_process
regulation of signal transduction
gene expression
regulation of neuron projection development
ventricular system development
layer formation in cerebral cortex
pyramidal neuron differentiation
cerebral cortex development
neurogenesis
central nervous system myelination
corpus callosum development
adult behavior
ciliary basal body organization
axoneme assembly
social behavior
neuronal stem cell division
protein kinase C deactivation
regulation of protein complex assembly
regulation of MAPK cascade
protein kinase B signaling
motile cilium assembly
positive regulation of smoothened signaling pathway
regulation of JNK cascade
cognition
dendritic spine development
cerebrospinal fluid circulation
GABAergic neuron differentiation
neuroinflammatory response
regulation of p38MAPK cascade
regulation of neuron migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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