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Invitrogen
NUP160 Polyclonal Antibody
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Product Details
PA5-20565
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 14 amino acid peptide from near the carboxy terminus of human NUP160.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is A549 cell lysate.
PA5-20565 can be used with blocking peptide PEP-0685.
Target Information
The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 160 kDa nucleoporin; Gene trap locus 1-13 protein; gene trap locus-13; GTL-13; Nuclear pore complex protein Nup160; nucleoporin 160kD; nucleoporin 160kDa; Nucleoporin Nup160; unnamed protein product
Gene Aliases: 160kDa; 2810011M03Rik; AA414952; AU020188; Gtl-13; Gtl1-13; Gtl13; KIAA0197; mKIAA0197; NPHS19; NUP120; NUP160
UniProt ID: (Human) Q12769, (Mouse) Q9Z0W3
Entrez Gene ID: (Human) 23279, (Mouse) 59015, (Rat) 311182
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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