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Invitrogen
CACNA2D2 Polyclonal Antibody
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FIGURE: 1 / 4
CACNA2D2 Antibody (PA5-35132) in ICC/IF
Immunocytochemistry analysis of U251 cells stained with CACNA2D2 (center). U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with CACNA2D2 polyclonal antibody (Product # PA5-35132) at a dilution of 1:25, for 1hr at 37&(8)451;. Followed by Conjugated Donkey anti-Rabbit secondary antibody, Alexa Fluor 488 (green) at a dilution of 1:400, for 50 minutes at 37&(8)451;. Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7 units/mL, 1hr at 37&(8)451;). CA... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-35132
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 643-671 amino acids from the central region of human CACNA2D2
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
800 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a2d-2; alpha 2 delta calcium channel subunit; alpha2delta-2; calcium channel, voltage-dependent, alpha 2/delta subunit 2; Cav alpha2/delta2; ducky; gene 26; protein ducky; regulatory subunit; unnamed protein product; voltage-dependent calcium channel alpha2/delta-2; voltage-gated calcium channel subunit alpha-2/delta-2
Gene Aliases: a2d2; CACNA2D; CASVDD; du; mKIAA0558; td; torpid
UniProt ID: (Human) Q9NY47, (Mouse) Q6PHS9
Entrez Gene ID: (Human) 9254, (Mouse) 56808
calcium ion transport
neuromuscular junction development
regulation of multicellular organism growth
positive regulation of organ growth
muscle cell development
rhythmic synaptic transmission
calcium ion transmembrane transport
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
positive regulation of muscle contraction
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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