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IL17RB Polyclonal Antibody
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FIGURE: 1 / 2
IL17RB Antibody (PA5-47051) in IHC (P)
Immunohistochemical analysis of IL17RB in perfusion fixed frozen sections of mouse spleen. Samples were incubated with IL17RB Polyclonal Antibody (Product # PA5-47051) using a dilution of 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG HRP Secondary Antibody. Tissue was stained with DAB (brown) and counterstained with hematoxylin (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-47051
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-17RB Arg18-Gly286
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL once reconstituted
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant mouse IL-17 R and recombinant human IL-17 R is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ecotropic viral integration site 27; Evi27A; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL-17RB; IL-20; interleukin 17B receptor; MGC138900; MGC138901; MGC5245; unnamed protein product; ZCYTO7
Gene Aliases: Evi27; IL-17ER; IL-17Rh1; Il17br; IL17RH1
UniProt ID: (Mouse) Q9JIP3
Entrez Gene ID: (Mouse) 50905
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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