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Invitrogen
AHCY Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-92380
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.86 mg/mL
Amount
86 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: 22Rv1, SW480, HepG2, U-937, SW620, MCF7, K-562, Mouse liver; Cellular Location: Cytoplasm, Melanosome
Immunogen sequence: AMEGYEVTTM DEACQEGNIF VTTTGCIDII LGRHFEQMKD DAIVCNIGHF DVEIDVKWLN ENAVEKVNIK PQVDRYRLKN GRRIILLAEG RLVNLGCAMG HPSFVMSNSF TNQVMAQIEL WTHPDKYPVG VHFLPKKLDE AVAEAHLGKL NVKLTKLTEK QAQYLGMSCD GPFKPDHYRY
Target Information
S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetylation; adoHcyase; epididymis secretory sperm binding protein; Hydrolase; liver copper-binding protein; NAD; Polymorphism; S-adenosyl-L-homocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase (EC 3.3.1.1); S-adenosylhomocysteine hydrolase; unnamed protein product
Gene Aliases: adoHcyase; CuBP; SAHH
UniProt ID: (Human) P23526, (Rat) P10760, (Mouse) P50247
Entrez Gene ID: (Human) 191, (Rat) 29443, (Mouse) 269378
S-adenosylmethionine cycle
response to hypoxia
chronic inflammatory response to antigenic stimulus
cellular modified amino acid metabolic process
sulfur compound metabolic process
response to nutrient
S-methylmethionine cycle
cellular modified amino acid catabolic process
circadian sleep/wake cycle
selenium compound metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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