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EGFR (ErbB1) [L858R] Recombinant Human Protein

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Description

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Gene ID: 1956, 7124
Species: Human
Target Gene: epidermal growth factor receptor
Gene Aliases: EGFR (ErbB1) L858R
Kinase Group: Tyrosine Kinases
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Receptor Tyrosine Kinases
Accession Number: NP_005219.2; L858R
Molecular Weight: 90.5 kDa
Research Category: Signal Transduction, Oncology
System Compatibility: LanthaScreen® Substrate, Omnia® Bulk Substrate, LanthaScreen® Antibody, Z'-LYTE™
Protein Tag or Fusion: GST Tag
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 668-1210: L858R
Expression: Baculovirus
Kinase Family: EGF Receptor (ErbB) Kinase Family
Protein Form: Recombinant, Cytoplasmic
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols