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ACVR1B (ALK4) Recombinant Human Protein

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Description

ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004293
Assay Entry: Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Kinase Group: Ser⁄Thr Kinases: TKL Group
Shipping Condition: Dry Ice
System Compatibility: Z'-LYTE™
Target Entry: ACVR1B
Target Gene: activin A receptor, type IB
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 3458, 91
Molecular Weight: 68.2 kDa
Gene Alias: ACVR1B (ALK4)
KinaseFamily: STKR Kinase Family
Protein Length: aa 150-505
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton® X-100, 2 mM DTT, and 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.