JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
For Research Use Only. Not for use in diagnostic procedures.
Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)