Thermo Scientific™

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

Catalog number: PV4336
Thermo Scientific™

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

Catalog number: PV4336
Catalog Number
PV4336
Unit Size
10 µg
Price (USD)
Price: 499.00
Your Price:
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Unit Size
100 µg
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Price: 2,905.00
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Unit Size
1 mg
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Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV433610 µg
Price: 499.00
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PR8134A100 µg
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Product Overview
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FAQ
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Additional Information
Recommendations
JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_004963
Gene ID (Entrez)
3717
Molecular Weight
97.9 kDa
Purity
70% by SDS-PAGE
Quantity
10 µg
Gene Alias
JAK2 JH1 JH2 V617F
KinaseFamily
JAK Kinase Family
Protein Length
aa 532-1132; V617F
Host Species
Insect
Recombinant
Yes
Protein Tag
GST Tag
Assay Entry
Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate
Target Entry
JAK2 JH1 JH2 V617F
Target Gene
Janus kinase 2
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Catalytic Domain, Cytoplasmic, Mutant
Form
Liquid
Protein Subtype
Cytoplasmic Tyrosine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Signal Transduction

Contents & Storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.