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JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

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JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
For Research Use Only. Not for use in diagnostic procedures.


Gene ID: 3717
Species: Human
Target Gene: Janus kinase 2
Gene Aliases: JAK2 JH1 JH2 V617F
Product Size: 10 µg
Protein Form: Catalytic, Cytoplasmic, Recombinant
Protein Family: Kinases & Inhibitors
Protein Subtype: Cytoplasmic Tyrosine Kinases
Accession Number: NP_004963
Molecular Weight: 97.9 kDa
Research Category: Signal Transduction
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Omnia® Bulk Substrate, Z'-LYTE™
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 532-1132; V617F
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: JAK Kinase Family
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols