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FRAP1 (mTOR) Recombinant Human Protein

Catalog number: PV4753

FRAP1 (mTOR) Recombinant Human Protein

Catalog number: PV4753
Catalog Number
PV4753
Unit Size
10 µg
Price (USD)
952.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV475310 µg
952.00
Your Price:
***
Product Overview
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FAQ
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Additional Information
Recommendations
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.

Specifications

Accession Number
NP_004949.1
Assay Entry
Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group
Ser⁄Thr Kinases: Atypical
Shipping Condition
Dry Ice
System Compatibility
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Target Entry
mTOR, FRAP1
Target Gene
FK506 binding protein 12-rapamycin associated protein 1
Expression System
Baculovirus
Form
Liquid
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Catalytic
Protein Subtype
Serine⁄Threonine Kinases
Research Category
Signal Transduction, Drug Development, Oncology
Species
Human
Validated Application
Kinase Assay
Molecular Weight
163.9 kDa
Quantity
10μg
Gene Alias
FRAP1 (mTOR)
KinaseFamily
PIKK Kinase Family
Protein Length
aa 1360-2549
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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Frequently asked questions (FAQs)

Citations & References