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FRAP1 (mTOR) Recombinant Human Protein

Catalog number: PV4753

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Species: Human
Target Gene: FK506 binding protein 12-rapamycin associated protein 1
Gene Aliases: FRAP1 (mTOR)
Kinase Group: Ser⁄Thr Kinases: Atypical
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_004949.1
Molecular Weight: 163.9 kDa
Research Category: Signal Transduction, Oncology
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Z'-LYTE™
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 1360-2549
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: PIKK Kinase Family
Protein Form: Catalytic, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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