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FRAP1 (mTOR) Recombinant Human Protein

Catalog number:  PV4753

Related applications:

Protein Biology

| Industrial & Applied Science

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Description

FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004949.1
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Ser⁄Thr Kinases: Atypical
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™
Target Entry: mTOR, FRAP1
Target Gene: FK506 binding protein 12-rapamycin associated protein 1
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Catalytic
Protein Subtype: Serine⁄Threonine Kinases
Research Category: Signal Transduction, Drug Development, Oncology
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 163.9 kDa
Quantity: 10μg
Gene Alias: FRAP1 (mTOR)
KinaseFamily: PIKK Kinase Family
Protein Length: aa 1360-2549
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.