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OriGene
LHX4 Monoclonal Antibody (OTI4E11), TrueMAB™
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FIGURE: 1 / 2
LHX4 Antibody (TA809561) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LHX4 (RC204014, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LHX4. (1. Positive lysates LY403244 (100 µg) and LC403244 (20 µg) can be purchased separately from OriGene.
Product Details
TA809561
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4E11
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-260 of human LHX4 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LHX4; LIM homeobox protein 4; LIM/homeobox protein Lhx4
Gene Aliases: CPHD4; LHX4
UniProt ID: (Human) Q969G2
Entrez Gene ID: (Human) 89884
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
zinc ion binding
methyl-CpG binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
placenta development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
apoptotic process
motor neuron axon guidance
organ morphogenesis
medial motor column neuron differentiation
neuron differentiation
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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