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OriGene
ITGB4 Polyclonal Antibody
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FIGURE: 1 / 2
ITGB4 Antibody (TA890131S) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITGB4 (RC220541, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ITGB4. Positive lysates LY423633 (100 µg) and LC423633 (20 µg) can be purchased separately from OriGene.
Product Details
TA890131S
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein of human ITGB4
Conjugate
Form
Liquid
Concentration
2.87 mg/mL
Amount
86.1 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD antigen CD104; CD104; CD104 antigen; GP150; Integrin beta-4; unnamed protein product
Gene Aliases: AA407042; C230078O20; CD104; GP150; ITGB4; JEB5A; JEB5B
UniProt ID: (Human) P16144, (Mouse) A2A863, (Rat) Q64632
Entrez Gene ID: (Human) 3691, (Mouse) 192897, (Rat) 25724
autophagy
cell communication
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
response to wounding
cell migration
myelination in peripheral nervous system
hemidesmosome assembly
peripheral nervous system myelin formation
cell adhesion mediated by integrin
nail development
skin morphogenesis
filopodium assembly
mesodermal cell differentiation
cell motility
trophoblast cell migration
cell-cell adhesion
skin development
digestive tract development
renal system development
amelogenesis
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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