Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
Citations & References (5)
Thermo Scientific™

Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)

Thermo Scientific Pierce Sulfo-SMPBは、中程度の長さの芳香族スペーサーアーム（11.6オングストローム）の両端にNHSエステル基およびマレイミド反応基を含む水溶性のアミン基-スルフヒドリル基間架橋剤です。Sulfo-SMPBの特徴：•反応基：Sulfo-NHSエステルとマレイミド• 以下と反応：アミノ基およびスルフヒドリル基• 長いスペーサーアームにより立体障害を軽減•詳細を見る
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製品番号（カタログ番号）数量
2231750 mg
製品番号（カタログ番号） 22317
価格（JPY）
50,000
Each
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数量:
50 mg
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Thermo Scientific Pierce Sulfo-SMPBは、中程度の長さの芳香族スペーサーアーム（11.6オングストローム）の両端にNHSエステル基およびマレイミド反応基を含む水溶性のアミン基-スルフヒドリル基間架橋剤です。

Sulfo-SMPBの特徴：

•反応基：Sulfo-NHSエステルとマレイミド
• 以下と反応：アミノ基およびスルフヒドリル基
• 長いスペーサーアームにより立体障害を軽減
• 非切断性
•水溶性（SMPBと比較）
• 膜非透過性、細胞表面の標識が可能

製品リファレンス：
架橋剤アプリケーションガイド - この製品に関する最近の文献参照を検索

関連製品
SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
研究用途にのみご使用ください。診断目的には使用できません。
仕様
細胞透過性No
概要Sulfo-SMPB
形状Powder
標識法化学的標識
分子量458.37
PEG化No
製品ラインPierce
数量50 mg
反応性部分マレイミド、Sulfo-NHSエステル
出荷条件Ambient
溶解性水
スペーサーアーム長11.6 Å
水溶性Yes
化学反応性Amine-Sulfhydryl
CleavableNo
クロスリンカータイプヘテロ三官能性
フォーマットStandard
製品タイプ架橋剤
スペーサー中程度の長さ
Unit SizeEach
組成および保存条件
受け取り後、-20℃で乾燥した場所に保存。製品は室温で出荷されます。

よくあるご質問（FAQ）

Can you provide the shelf-life for Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)?

Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用および参考文献 (5)

引用および参考文献
Abstract
pICln inhibits snRNP biogenesis by binding core spliceosomal proteins.
Authors:Pu WT, Krapivinsky GB, Krapivinsky L, Clapham DE
Journal:Mol Cell Biol
PubMed ID:10330151
'The U1, U2, U4, U5, and U6 small nuclear ribonucleoproteins (snRNPs) form essential components of spliceosomes, the machinery that removes introns from pre-mRNAs in eukaryotic cells. A critical initial step in the complex process of snRNP biogenesis is the assembly of a group of common core proteins (Sm proteins) on ... More
Substrate-induced conformational change in bacterial complex I.
Authors:Mamedova AA, Holt PJ, Carroll J, Sazanov LA
Journal:J Biol Chem
PubMed ID:15037611
'The mechanism coupling electron transfer and proton pumping in respiratory complex I (NADH-ubiquinone oxidoreductase) has not been established, but it has been suggested that it involves conformational changes. Here, the influence of substrates on the conformation of purified complex I from Escherichia coli was studied by cross-linking and electron microscopy. ... More
Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis.
Authors:Zhu JX, Goldoni S, Bix G, Owens RT, McQuillan DJ, Reed CC, Iozzo RV
Journal:J Biol Chem
PubMed ID:15994311
Decorin inhibits the epidermal growth factor receptor (EGFR) by down-regulating its tyrosine kinase activity, thereby blocking the growth of a variety of transformed cells and tumor xenografts. In this study we provide evidence that decorin directly binds to the EGFR causing its dimerization, internalization, and ultimately its degradation. Using various ... More
Combination of DNA-directed immobilization and immuno-PCR: very sensitive antigen detection by means of self-assembled DNA-protein conjugates.
Authors:Niemeyer CM, Wacker R, Adler M
Journal:Nucleic Acids Res
PubMed ID:12907742
An assay for very sensitive antigen detection is described which takes advantage of the self- assembly capabilities of semi-synthetic conjugates of DNA and proteins. The general scheme of this assay is similar to a two-sided (sandwich) enzyme-linked immunoassay (ELISA); however, covalent single-stranded DNA-streptavidin (STV) conjugates, capable of hybridizing to complementary ... More
Biologically active decorin is a monomer in solution.
Authors:Goldoni S, Owens RT, McQuillan DJ, Shriver Z, Sasisekharan R, Birk DE, Campbell S, Iozzo RV
Journal:J Biol Chem
PubMed ID:14660661
It has been reported that decorin and its protein core can have molecular masses nearly double the size of those previously published, suggesting a dimeric structure. In this study we tested whether biologically active decorin and its glycoprotein core would form dimers in solution. We used homo- and hetero-bifunctional chemical ... More