BAPTA, Tetracesium Salt, cell impermeant

BAPTAは細胞不透過性キレート剤で、Mg2+を超えるCa 2+ に対して高い選択性を有しており、細胞外Ca 2+のレベルを制御するために使用できます。BAPTAは、EDTAやEGTAよりもCa2+に対して選択的であり、金属結合もpHに対して感度が低くなります。カルシウム詳細を見る

製品番号（カタログ番号）	数量
B1212	1 g

製品番号（カタログ番号） B1212

価格（JPY）

84,800

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BAPTAは細胞不透過性キレート剤で、Mg²⁺を超えるCa ²⁺ に対して高い選択性を有しており、細胞外Ca ²⁺のレベルを制御するために使用できます。BAPTAは、EDTAやEGTAよりもCa²⁺に対して選択的であり、金属結合もpHに対して感度が低くなります。

カルシウム、カリウム、pH、膜電位インジケータなどのイオンインジケータの詳細をご覧ください›

研究用にのみ使用できます。診断用には使用いただけません。

染色剤タイプキレート剤（非蛍光）

数量1 g

出荷条件室温

製品タイプ細胞の生存率と増殖

Unit SizeEach

組成および保存条件

室温保存。

引用および参考文献 (22)

引用および参考文献

Abstract

Neurosteroids modulate calcium currents in hippocampal CA1 neurons via a pertussis toxin-sensitive G-protein-coupled mechanism.

Authors:ffrench-Mullen JM, Danks P, Spence KT

Journal:J Neurosci

PubMed ID:8158251

'The inhibition of Ca2+ channel currents by endogenous brain steroids was examined in freshly dissociated pyramidal neurons from the adult guinea pig hippocampal CA1 region. The steady-state inhibition of the peak Ca2+ channel current evoked by depolarizing steps from -80 to -10 mV occurred in a concentration-dependent manner with the ... More

Calcium-induced inactivation of NMDA receptor-channels evolves independently of run-down in cultured rat brain neurones.

Authors:Medina I, Filippova N, Bakhramov A, Bregestovski P

Journal:J Physiol

PubMed ID:8887753

'1. Calcium-induced transient inactivation of NMDA receptor (NMDAR) channels was studied in cultured rat hippocampal and cerebellar granule neurones using patch-clamp techniques and confocal scanning microscopy. 2. During whole-cell recordings, in the presence of 2 mM external Ca2+, conditioning (2-20 s) pulses of NMDA (20-100 microM) caused a transient decrease ... More

A store-operated calcium channel in Drosophila S2 cells.

Authors:Yeromin AV, Roos J, Stauderman KA, Cahalan MD

Journal:J Gen Physiol

PubMed ID:14744989

'Using whole-cell recording in Drosophila S2 cells, we characterized a Ca(2+)-selective current that is activated by depletion of intracellular Ca2+ stores. Passive store depletion with a Ca(2+)-free pipette solution containing 12 mM BAPTA activated an inwardly rectifying Ca2+ current with a reversal potential >60 mV. Inward currents developed with a ... More

Ca2+ store dynamics determines the pattern of activation of the store-operated Ca2+ current I(CRAC) in response to InsP3 in rat basophilic leukaemia cells.

Authors:Glitsch MD, Parekh AB

Journal:J Physiol

PubMed ID:10699074

'1. The relationship between the amplitude of the store-operated Ca2+ ICR AC and intracellular inositol 1,4,5-triphosphate (InsP3) concentration is complex. In rat basophilic leukaemia (RBL-1) cells dialysed with high intracellular Ca2+ buffer, the relationship is supra-linear with a Hill coefficient of 12 and resembles an apparent ''all-or-none'' phenomenon. The non-linearity ... More

Phosphorylation of RIM1alpha by PKA triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses.

Authors:Lonart G, Schoch S, Kaeser PS, Larkin CJ, Südhof TC, Linden DJ

Journal:Cell

PubMed ID:14532002

'Presynaptic activation of protein kinase A (PKA) induces LTP in cerebellar parallel fiber synapses. Presynaptic LTP is known to require the active zone protein RIM1alpha, but the underlying induction mechanism remains unclear. We now show that PKA directly phosphorylates RIM1alpha at two sites. Using paired recordings from cultured cerebellar granule ... More

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