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Invitrogen
Claudin 6 Recombinant Human Monoclonal Antibody (6D4)
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FIGURE: 1 / 3
Claudin 6 Antibody (MA5-60731) in Flow
Flow cytometry of Claudin 6 in untransfected HEK-293T cells (green line) and transfected Human CLDN6 HEK-293T stable cells (red line). Samples were incubated with Claudin 6 Recombinant Monoclonal antibody (Product # MA5-60731) followed by APC-conjugated anti-Human IgG Fc.
Product Details
MA5-60731
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
6D4
Immunogen
Recombinant Human CLDN6 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Claudin-6; Claudin6; CLD6; Skullin; transmembrane protein; unnamed protein product
Gene Aliases: CLDN6; UNQ757/PRO1488
UniProt ID: (Human) P56747
Entrez Gene ID: (Human) 9074
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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