Search
Invitrogen
pro-Kallikrein 5 Monoclonal Antibody (325302)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-60921
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
325302
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Kallikrein 5, Val23-Arg66
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Pro-Kallikrein 5 (KLK5) is a member of the kallikrein-related peptidase family, which comprises serine proteases involved in various physiological processes. KLK5 is encoded by the KLK5 gene located on chromosome 19 in humans. This enzyme is initially synthesized as an inactive zymogen, pro-Kallikrein 5, and is activated through proteolytic cleavage. KLK5 plays a critical role in skin desquamation, the process of shedding dead skin cells, by degrading intercellular adhesive proteins in the epidermis. It is also implicated in the regulation of inflammation and immune responses. Abnormal expression or activity of KLK5 has been linked to skin disorders such as Netherton syndrome and atopic dermatitis, as well as certain cancers. Due to its involvement in these conditions, KLK5 is being studied as a potential biomarker and therapeutic target for disease diagnosis and treatment. Understanding the regulation and function of KLK5 can provide insights into skin homeostasis and the pathogenesis of related diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support