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Invitrogen
ACTA1 Monoclonal Antibody (AC-40)
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Product Details
MA5-32995
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
AC-40
Immunogen
Synthetic actin C-terminal peptideSer-Gly-Pro-Ser-Ile-Val-His-Arg-Lys-Cys-Phe, attached to a Multiple Antigen Peptide (MAP) backbone.
Conjugate
Form
Lyophilized
Concentration
100 µg/mL
Amount
100 µg
Storage buffer
ascites/1.2% sodium acetate with 2mg BSA
Contains
0.01mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute by adding 1 mL of PBS buffer, yielding a concentration of 100 µg/mL.
Positive Control - WB: human HEK293 whole cell, rat PC-12 whole cell, mouse NIH3T3 cell IHC-F: Mouse Intestine Tissue, Human Placenta Tissue, Rat Spleen Tissue, Mouse Spleen Tissue, Rat Intestine Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a-actin; ACTA1; actin alpha 1; Actin, alpha skeletal muscle; alpha-actin; Alpha-actin-1; nemaline myopathy type 3; unnamed protein product
Gene Aliases: AA959943; ACTA; Acta-2; ACTA1; Acts; Actsk-1; ASMA; CFTD; CFTD1; CFTDM; CMYO2A; CMYO2B; CMYO2C; CMYP2A; CMYP2B; CMYP2C; MPFD; NEM1; NEM2; NEM3; SHPM
UniProt ID: (Human) P68133, (Chicken) P68139, (Mouse) P68134, (Rat) P68136
Entrez Gene ID: (Human) 58, (Chicken) 421534, (Mouse) 11459, (Rat) 29437
muscle contraction
positive regulation of gene expression
skeletal muscle thin filament assembly
skeletal muscle fiber development
mesenchyme migration
response to mechanical stimulus
response to extracellular stimulus
response to lithium ion
cell growth
skeletal muscle fiber adaptation
response to steroid hormone
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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