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Invitrogen
GnRH1 Polyclonal Antibody
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Product Details
PA1-121
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Amphibian,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-121 detects gonadotropin releasing hormone (GnRH) in mouse brain and in amphibian (Hyla cinerea) samples.
PA1-121 has been successfully used in immunohistochemistry procedures. Immunohistochemical staining of GnRH in mouse embryo brain tissue using PA1-121 results in staining of neurons in the organum vasculosum of the lamina terminalis (OVLT).
In immunohistochemical procedures, 4% paraformaldehyde is recommended as a fixative.
The PA1-121 immunogen is a synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH. This sequence is completely conserved in rat and tree shrew and is 78% conserved in zebrafish. The PA1-121 immunizing peptide (Cat. # PEP-168) is available for use in neutralization and control experiments.
Target Information
The Luteinizing Hormone Releasing Hormone (LH-RH) is produced in the hypothalamus and influences the release of Luteinizing Hormone in the pituitary gland. LH-RH is also known as Gonadotropin-releasing hormone (Gn-RH).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: gonadotropin releasing hormone 2; hypogonadal; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; Progonadoliberin-1
Gene Aliases: Gnrh; Gnrh1; Gnrh2; hpg; LHRH; Lhrh1; Lnrh
UniProt ID: (Mouse) P13562
Entrez Gene ID: (Mouse) 14714
multicellular organism development
regulation of gene expression
male sex determination
negative regulation of immature T cell proliferation
negative regulation of apoptotic process
response to ethanol
response to steroid hormone
regulation of ovarian follicle development
negative regulation of neuron migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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