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          • Primary Antibodies ›
          • GP1BB Antibodies

          Invitrogen

          GP1BB Polyclonal Antibody

          View all (4) GP1BB antibodies

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          Cite GP1BB Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          GP1BB Antibody in Western Blot (WB)
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          GP1BB Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          GP1BB Antibody (PA5-22267) in WB

          Western Blot using GP1BB Polyclonal Antibody (Product # PA5-22267). Sample (30 µg of whole cell lysate). Lane A: Raji. 12% SDS PAGE. GP1BB Polyclonal Antibody (Product # PA5-22267) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          GP1BB Antibody in Western Blot (WB)

          Product Details

          PA5-22267

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide encompassing a sequence within the Extracellular domain of human CD42c. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.75 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11157436

          Product Specific Information

          Recommended positive controls: Raji.

          Predicted reactivity: Mouse (100%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryoctes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand's factor and as a von Willebrand's factor-dependent adhesion receptor.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Antigen CD42b-beta; CD42c; glycoprotein Ib (platelet), beta polypeptide; glycoprotein Ib platelet beta subunit; GP-Ib beta; GPIb-beta; GPIbB; nuclear localization signal deleted in velocardiofacial syndrome; Platelet glycoprotein Ib beta chain; platelet glycoprotein Ib beta chain precursor; platelet membrane glycoprotein Ib beta

          View more View less

          Gene Aliases: BDPLT1; BS; CD42C; GP1BB; GPIBB; GPIbbeta

          View more View less

          UniProt ID: (Human) P13224, (Mouse) P56400

          View more View less

          Entrez Gene ID: (Human) 2812, (Mouse) 14724

          View more View less

          Function(s)
          transmembrane signaling receptor activity protein binding identical protein binding
          Process(es)
          cell adhesion cell surface receptor signaling pathway blood coagulation blood coagulation, intrinsic pathway hemostasis positive regulation of platelet activation platelet activation megakaryocyte development release of sequestered calcium ion into cytosol
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

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          Host server : magellan-search-green-7d94cb4b65-mrft7:80/100.66.76.145:80.
          git-commit: c9e08c96761173abe34e68f880379696776a4827
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