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Invitrogen
IFT88 Polyclonal Antibody
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Product Details
PA5-88948
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
2.69 mg/mL
Amount
269 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GLTYEKLNRL DEALDCFLKL HAILRNSAEV LYQIANIYEL MENPSQAIEW LMQVVSVIPT DPQVLSKLGE LYDREGDKSQ AFQYYYESYR YFPCNIEVIE WLGAYYIDTQ FWEKAIQYFE RASLIQPTQV KWQLMVASCF RRSGNYQKAL DTYKDTHRKF PENVECLRFL VRLCTDLGLK DAQEYARKLK RLEKMKEIRE QRIKSGRDGS GGSRGKREGS ASGDSGQNYS ASSKGERLSA RLRALPGTNE PYESSSNKEI DASYVDPLGP QIERPKTAAK KRIDEDDFAD EELGDDLLPE; Positive Samples: HepG2, BxPC-3, Mouse brain, Mouse eye; Cellular Location: Cytoplasm, centriole, centrosome, cilium basal body, cytoskeleton, microtubule organizing center
Target Information
This gene encodes a member of the tetratrico peptide repeat family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:20606; intraflagellar transport 88 homolog; Intraflagellar transport protein 88 homolog; MGC26259; mutations in the mouse Tg737 gene cause polycystic kidney disease; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); Recessive polycystic kidney disease protein Tg737; Recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; Tetratricopeptide repeat protein 10; Tg737 protein; TgN(Imorpk)737Rpw; TPR repeat protein 10; transgene insert site 737, insertional mutation, polycystic kidney disease; unnamed protein product
Gene Aliases: AW552028; D13S1056E; DAF19; flexo; fxo; hTg737; IFT88; orpk; polaris; TG737; Tg737Rpw; TgN737Rpw; TTC10
UniProt ID: (Human) Q13099, (Mouse) Q61371
Entrez Gene ID: (Human) 8100, (Mouse) 21821
eye development
kidney development
liver development
epithelial cell morphogenesis
Notch signaling pathway
smoothened signaling pathway
sperm axoneme assembly
spermatid nucleus elongation
determination of left/right symmetry
nervous system development
brain development
heart development
protein localization
epidermis development
regulation of smoothened signaling pathway
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
spinal cord dorsal/ventral patterning
telencephalon development
cell projection organization
lung development
pancreas development
cytoplasmic microtubule organization
response to fluid shear stress
nonmotile primary cilium assembly
epidermal stem cell homeostasis
cilium assembly
regulation of odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of insulin-like growth factor receptor signaling pathway
regulation of fat cell differentiation
forebrain morphogenesis
negative regulation of epithelial cell proliferation
cardiac muscle cell differentiation
palate development
inner ear receptor stereocilium organization
limb development
regulation of feeding behavior
cilium morphogenesis
cardiac septum morphogenesis
lung vasculature development
heart formation
neural precursor cell proliferation
regulation of protein processing
cochlea development
regulation of cilium assembly
regulation of autophagosome assembly
response to silicon dioxide
intraciliary anterograde transport
intraciliary transport
positive regulation of cilium assembly
non-motile cilium assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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