Search
Invitrogen
BRCA2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-96128
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment).
Conjugate
Form
Liquid
Concentration
0.79 mg/mL
Amount
79 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: 293T; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center
Target Information
Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumor-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: brca 2; brca-2; BRCA1/BRCA2-containing complex, subunit 2; BRCA2 DNA repair associated protein; breast and ovarian cancer susceptibility gene, early onset; breast and ovarian cancer susceptibility protein 2; breast cancer 2 tumor suppressor; breast cancer 2, early onset; breast cancer 2, mutation 1, University of Wisconsin-Madison; breast cancer susceptibility protein 2; Breast cancer type 2 susceptibility protein; Breast cancer type 2 susceptibility protein homolog; DNA repair associated; DNA repair-associated BRCA2; FANCB; Fanconi anemia group D1 protein; Fanconi anemia group D1 protein homolog; mutant BRCA2; mutant DNA repair-associated protein 2; RP11-298P3.4
Gene Aliases: BRCA2; BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; RAB163; XRCC11
UniProt ID: (Human) P51587, (Mouse) P97929
Entrez Gene ID: (Human) 675, (Mouse) 12190, (Rat) 360254
telomere maintenance via recombination
double-strand break repair via homologous recombination
oocyte maturation
inner cell mass cell proliferation
DNA repair
nucleotide-excision repair
double-strand break repair
DNA recombination
chromatin remodeling
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
male meiosis I
spermatogenesis
brain development
cell proliferation
female gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
response to X-ray
response to UV-C
response to gamma radiation
hemopoiesis
DNA damage response, signal transduction by p53 class mediator
replication fork processing
regulation of cytokinesis
negative regulation of mammary gland epithelial cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
chordate embryonic development
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
chromosome organization
centrosome duplication
establishment of protein localization to telomere
hematopoietic stem cell proliferation
cellular response to ionizing radiation
stem cell proliferation
cellular senescence
mitotic recombination-dependent replication fork processing
regulation of DNA damage checkpoint
cytokinesis
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
cell cycle
cell aging
mammary gland development
chromosome breakage
homologous chromosome orientation involved in meiotic metaphase I plate congression
multicellular organism growth
regulation of cell proliferation
histone H3 acetylation
histone H4 acetylation
replication fork protection
response to nutrient
response to estradiol
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support