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Gibco
Mouse CXCL1 (GRO alpha) Recombinant Protein, PeproTech®
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Product Details
250-11-250UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Published species
Bacteria,
Fungi,
Human,
Mouse
Expression System
E. coli
Amino acid sequence
APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK
Molecular weight
7.8 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.
Conjugate
Form
Lyophilized
Amount
250 µg
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
250-11-1MG will be provided as 2 x 500 µg (250-11-500UG).
Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha-chemokine; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 1; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; CXCL-1; GRO a; GRO α; GRO1 oncogene; GROalpha; Growth-regulated alpha protein; GROα; KC/GR)-alpha; KC/GRO-alpha; NAP3; Platelet-derived growth factor-inducible protein KC; Secretory protein N51
Gene Aliases: Cxcl1; Fsp; Gro; Gro1; KC; Mgsa; N51; Scyb1
UniProt ID: (Mouse) P12850
Entrez Gene ID: (Mouse) 14825
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