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Product Details
PEP-0977
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human INCA1.
PEP-0977 can be used as a blocking peptide with polyclonal antibody PA5-20863.
Target Information
Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor (PubMed:21540187). Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Inhibitor of CDK interacting with cyclin A1; Protein INCA1
Gene Aliases: HSD45; INCA1
UniProt ID: (Human) Q0VD86
Entrez Gene ID: (Human) 388324
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