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Invitrogen
Human MYBPC2 (aa 89-179) Control Fragment Recombinant Protein
Product Details
RP-98873
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKSDTA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).^M
^M
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83638. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The gene MYBPC2 belongs to the myosin-binding protein C family, which consists of fast-, slow-, and cardiac-type isoforms. These isoforms are myosin-associated proteins that are located in the C region of A bands in striated muscle. The protein encoded by MYBPC2 is the fast-type isoform. Mutations in genes encoding the slow-type and cardiac-type isoforms have been linked to distal arthrogryposis, type 1, and hypertrophic cardiomyopathy, respectively. MYBPC2-related diseases include Lethal Congenital Contracture Syndrome 4 and Nemaline Myopathy 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-protein, skeletal muscle fast isoform; Fast MyBP-C; fast-type muscle myosin-binding-protein C; Myosin-binding protein C, fast-type; mypc2; testicular tissue protein Li 126
Gene Aliases: MYBPC; MYBPC2; MYBPCF
UniProt ID: (Human) Q14324
Entrez Gene ID: (Human) 4606
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