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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65665. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATR2; DNA repair and recombination protein RAD54-like; h hRAD54; hHR54; MGC2094; MRXHF1; RAD54 homolog; RP5-875J14.1; SFM1; SHS; XH2; XNP; ZNF-HX
Gene Aliases: hHR54; HR54; hRAD54; RAD54A; RAD54L
UniProt ID: (Human) Q92698
Entrez Gene ID: (Human) 8438
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