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Product Details
RP-108539
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QFSKRYLKYLTKKYLKKNNLRDWLRVVAS
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84777. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Ribosomal Protein L22 is also known as heparin-binding protein HBp15, because it binds heparin in the submandibular gland and brain. This small protein is also associated with two small nuclear RNAs called EBERs (Epstein- Barr encoded RNAs). These RNAs are synthesized in large amounts by human B lymphocytes infected with Epstein-Barr virus (EBV). Ribosomal protein L22, like L4, contains a globular domain that sits on the surface of the large ribosomal subunit and an extended loop that penetrates its core. These extensions contact multiple domains of 23S rRNA, indicating a potential, but not essential, role in rRNA folding during ribosomal assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L22-like 1; Large ribosomal subunit protein eL22-like 1; Ribosomal protein eL22-like; ribosomal protein L22-like 1; RPL22
Gene Aliases: RPL22L1
UniProt ID: (Human) Q6P5R6
Entrez Gene ID: (Human) 200916
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