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Gibco
Rat IFN-beta Recombinant Protein
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Product Details
PRC4024
Product Specifications
Expression System
CHO cells
Class
Recombinant
Type
Protein
Conjugate
Form
Lyophilized
Storage conditions
4°C
Shipping conditions
Wet ice (domestic); Wet or Dry ice (international)
Product Specific Information
Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute with 0.2 mL sterile, distilled water.
Storage: The lyophilized protein may be stored at 2°C to 8°C. Upon reconstitution, the protein should be apportioned into working aliquots and stored at -80°C. Avoid repeated freeze-thaw cycles. The reconstituted protein will only remain bioactive for up to two weeks when stored at 2°C to 8°C.
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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