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Antibodies Inc
mGluR1/5 (Group I) Glutamate Receptor Monoclonal Antibody (N75/33), FL490
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Product Details
75-116-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N75/33
Immunogen
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b (accession number P31424) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
may play a role in synaptic transmission; may interact with mGluR1, another group I metabotropic glutamate receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member E; glutamate receptor; glutamate receptor, metabotropic 1; glutamate receptor, metabotropic 5; GPCR family C; metabotropic glutamate receptor (mGluR5); Metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5 homolog; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; mGluR1; mGluR5; mGluR5f; mGluR5g; mGluR5h; mGluR5i; mGlurR1a; protein phosphatase 1, regulatory subunit 85; protein phosphatase 1, regulatory subunit 86; unnamed protein product
Gene Aliases: 4930455H15Rik; 6430542K11Rik; AI850523; ENSMUSG00000075319; Glu5R; Gm10828; GPRC1A; GPRC1E; GRM1; GRM5; MGLU1; mGlu5; MGLUR1; MGLUR5; mGluR5b; nmf373; PPP1R85; PPP1R86; rcw; SCA44; SCAR13; wobl
UniProt ID: (Human) Q13255, (Human) P41594, (Mouse) P97772, (Rat) P23385, (Rat) P31424, (Mouse) Q3UVX5
Entrez Gene ID: (Human) 2911, (Human) 2915, (Mouse) 14816, (Rat) 24414, (Rat) 24418, (Mouse) 108071
adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
G-protein coupled receptor activity
protein binding
glutamate receptor activity
G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
protein tyrosine kinase activator activity
A2A adenosine receptor binding
identical protein binding
protein tyrosine kinase binding
PLC activating G-protein coupled glutamate receptor activity
signal transducer activity
estrogen receptor binding
calmodulin binding
PDZ domain binding
G-protein coupled receptor
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
sensory perception of pain
regulation of membrane potential
positive regulation of MAPK cascade
regulation of sensory perception of pain
regulation of synaptic transmission, glutamatergic
regulation of postsynaptic membrane potential
cellular response to electrical stimulus
L-glutamate import across plasma membrane
synaptic signaling via neuropeptide
regulation of postsynaptic cytosolic calcium ion concentration
desensitization of G-protein coupled receptor protein signaling pathway
regulation of transcription, DNA-templated
learning or memory
learning
regulation of long-term neuronal synaptic plasticity
positive regulation of long-term neuronal synaptic plasticity
modulation of synaptic transmission
synapse organization
positive regulation of calcium-mediated signaling
cognition
positive regulation of intracellular signal transduction
cellular response to beta-amyloid
activation of MAPKK activity
activation of MAPK activity
protein kinase C-activating G-protein coupled receptor signaling pathway
calcium-mediated signaling
dimeric G-protein coupled receptor signaling pathway
regulation of MAPK cascade
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
regulation of glutamate secretion
membrane depolarization
synaptic transmission, GABAergic
activation of MAPKKK activity
protein phosphorylation
negative regulation of locomotion
phosphatidylinositol-mediated signaling
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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