Invitrogen™

MET (cMET) Y1235D Recombinant Human Protein

Catalog number: A33505
Invitrogen™

MET (cMET) Y1235D Recombinant Human Protein

Catalog number: A33505
Catalog Number
A33505
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
2,115.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A3350510 µg
451.00
Your Price:
***
A337281 mg
6,570.00
Your Price:
***
A33559100 µg
2,115.00
Your Price:
***
Product Overview
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This MET (cMET) Y1235D recombinant human protein (956–end) was expressed in insect cells. MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue. Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion. MET (Y1235D) is one of the native mutant forms of MET. MET (cMET) Y1235D recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_000236.2
Shipping Condition
Dry Ice
Expression System
Insect
Form
Liquid
Protein Form
Recombinant, Active, Cytoplasmic, Mutant
Species
Human
Validated Application
Kinase Assay
Molecular Weight
75.4 kDa
Quantity
10 µg
KinaseFamily
METs (HGFRs)
Protein Length
aa 956 - 1390
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol

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Citations & References