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          • Primary Antibodies ›
          • SNRPB Antibodies

          Invitrogen

          SNRPB Monoclonal Antibody (Y12)

          Advanced Verification
          6 Published Figures
          28 References
          View all (7) SNRPB antibodies

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          Cite SNRPB Monoclonal Antibody (Y12)

          Additional Information:
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          • Antibody Testing Data (6)
          • Published Figures (6)
          • Advanced Verification (3)
          SNRPB Antibody in Immunocytochemistry (ICC/IF)
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          SNRPB Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 15

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          SNRPB Antibody (MA5-13449) in ICC/IF

          Immunofluorescence analysis of SNRPB was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with SNRPB Mouse monoclonal antibody (Product # MA5-13449) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A28175) at... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          SNRPB Antibody in Immunocytochemistry (ICC/IF)
          SNRPB Antibody in Immunocytochemistry (ICC/IF)
          SNRPB Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SNRPB Antibody in Western Blot (WB)
          SNRPB Antibody in Western Blot (WB)
          SNRPB Antibody in RNA Immunoprecipitation (RIP)
          SNRPB Antibody in Immunohistochemistry (Frozen) (IHC (F))
          SNRPB Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          SNRPB Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          SNRPB Antibody in Western Blot (WB)
          SNRPB Antibody in Western Blot (WB)
          SNRPB Antibody in Immunoprecipitation (IP)
          SNRPB Antibody
          SNRPB Antibody
          SNRPB Antibody

          Product Details

          MA5-13449

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.5-1.0 µg/mL
          View 6 publications 6 publications

          Immunohistochemistry (IHC)

          -
          View 5 publications 5 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:100
          -

          Immunohistochemistry (Frozen) (IHC (F))

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          2 µg/mL
          View 7 publications 7 publications

          Immunoprecipitation (IP)

          -
          View 8 publications 8 publications

          Proximity Ligation Assay (PLA) (PLA)

          -
          View 1 publication 1 publication

          Immunomicroscopy (IM)

          Assay-dependent
          -

          RNA Immunoprecipitation (RIP)

          1.5 µg/10^6 cells
          -
          Product Specifications

          Species Reactivity

          Fruit fly, Human, Mouse, Pig, Rabbit, Rat

          Published species

          Chicken, Dog, Flatworm, Fruit fly, Hamster, Human, Mouse, Rat

          Host/Isotype

          Mouse / IgG3, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          Y12

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • Biotin 
          • Request custom conjugation

          Form

          Liquid

          Concentration

          200 µg/mL

          Amount

          100 µg

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 0.2% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10944191

          Target Information

          The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: B polypeptide of Sm protein; Sm protein B; Sm protein B/B'; Sm-B; Sm-B/B'; sm-B/Sm-B'; SM11; small nuclear ribonucleoprotein particle (SmB'); small nuclear ribonucleoprotein particle (SmB); small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein-associated protein B; Small nuclear ribonucleoprotein-associated proteins B and B'; smB; snRNP polypeptide B; snRNP-B; SNRPB; unnamed protein product

          View more View less

          Gene Aliases: AL024368; AU018828; CCMS; COD; SM-B; Sm-B/B'; SM11; SMB; SmB/B'; SmB/SmB'; SNRNP-B; SNRPB; SNRPB1

          View more View less

          UniProt ID: (Human) P14678, (Mouse) P27048, (Rat) P17136

          View more View less

          Entrez Gene ID: (Human) 6628, (Rabbit) 100341600, (Mouse) 20638, (Rat) 171365

          View more View less

          Function(s)
          RNA binding protein binding telomerase RNA binding snRNP binding histone pre-mRNA DCP binding U1 snRNP binding U2 snRNP binding poly(A) RNA binding RNA splicing factor
          Process(es)
          spliceosomal snRNP assembly mRNA splicing, via spliceosome mRNA processing protein methylation RNA splicing 7-methylguanosine cap hypermethylation U2-type prespliceosome assembly positive regulation of defense response to virus by host mitophagy in response to mitochondrial depolarization
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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