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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: EEEVKKEADP GETPSEAPSE ARTTPAENGV NHTTTLTPKP PSQALHSQPA PGSVKAPAKT EDLIQSVLTE VEAQTIEELK QQKSFVK
Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 93%.
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; Phosphoinositide phospholipase C-beta-1; phosphoinositide-specific phospholipase c; Phospholipase C-beta-1; Phospholipase C-I; PLC-154; PLC-beta-1; PLC-I
Gene Aliases: KIAA0581; PLCB1
Entrez Gene ID: (Human) 23236
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