k74 Silk

k74 Silk Scientific Information

Type:

Whole Allergen

Display Name:

Silk

Allergen code:

k74

Latin Name:

Bombyx mori

Other Names:

Silk

Route of Exposure

Occupational

Cultured silk from Bombyx mori, is used for exclusive textiles. Workers in the silk industry are heavily exposed. In addition to pure silk they are exposed to silk waste containing potent contaminating allergens such as insect material(1).

Clinical Relevance

IgE-mediated reactions

Allergic respiratory symptoms are well known among silk industry workers and have been attributed to proteins from the silk worm(2). The substance glueing together the thread filaments, sericin, was previously suspected but this hypothesis has not been confirmed (1). Dust containing pure silk is not a potent allergen.

Compiled By

Last Reviewed- April 2022

References

Johansson SGO, Wüthrich B, Zortea-Caflisch C: Nightly asthma caused by allergens in silkfilled bed quilts: Clinical and immunological studies. J Allergy Clin Immunol 1985, 75, 452-459.
Kobayashi S: Occupational asthma due to inhalation of pharmacological dusts and other chemical agents with some reference to other occupational asthmas in Japan. In Allergology Proceedings VIII Int Congr Allergol eds. Y Yamamura et al., Exerpta Medica, Amsterdam 1973, 127-132.