ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
2310008D05Rik; endothelial cell adhesion molecule; Endothelial cell-selective adhesion molecule; HUEL (C4orf1)-interacting protein; LP4791 protein; W117m
Please enter the information below and press OK to send your cart to Core Services for purchase.