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Invitrogen
ESAM Polyclonal Antibody
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FIGURE: 1 / 3
ESAM Antibody (PA5-48019) in IHC (P)
Immunohistochemical analysis of ESAM in immersion fixed paraffin-embedded sections of mouse kidney. Samples were incubated with ESAM Polyclonal Antibody (Product # PA5-48019) using a dilution of 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG HRP Secondary Antibody. Tissue was stained with DAB (brown) and counterstained with hematoxylin (blue).
Product Details
PA5-48019
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse ESAM Gln30-Ser248 (predicted)
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant human ESAM is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endothelial cell-selective adhesion molecule
Gene Aliases: 2310008D05Rik; Esam; Esam1; W117m
UniProt ID: (Mouse) Q925F2
Entrez Gene ID: (Mouse) 69524
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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