ATP5F1A Antibodies

Target Information

The ATP5F1A gene (ATP Synthase F1 Subunit Alpha) is located on chromosome 18q21.33 and encodes a critical component of the mitochondrial ATP synthase complex, specifically the F1 catalytic core. The ATP synthase complex is essential for cellular energy production, facilitating the conversion of ADP to ATP during oxidative phosphorylation. The ATP5F1A subunit is responsible for the catalysis of ATP synthesis driven by the proton gradient across the inner mitochondrial membrane. Dysfunctions or mutations in ATP5F1A can result in mitochondrial disorders and are linked to various metabolic and neurodegenerative diseases. Understanding the structure and function of ATP5F1A is vital for comprehending the bioenergetics of cellular respiration and has implications in studying mitochondrial pathologies.

Synonyms

AI035633; AL022851; AL023067; alpha subunit ATP synthase isoform precursor (EC 3.6.1.34); ATP synthase alpha chain, mitochondrial; ATP synthase alpha subunit; ATP synthase alpha subunit precursor; ATP synthase F1 subunit alpha; ATP synthase subunit alpha heart isoform, mitochondrial; ATP synthase subunit alpha liver isoform, mitochondrial; ATP synthase subunit alpha, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2; ATP sythase (F1-ATPase) alpha subunit; ATP5A; Atp5a1; ATP5A2; ATP5AL2; ATP5F1A; atp5fa1; ATPM; cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1; COXPD22; D18Ertd206e; EGK_09658; epididymis secretory sperm binding protein Li 123m; hATP1; HEL-S-123m; iso; MC5DN4; mitochondrial ATP synthase alpha chain; mitochondrial ATP synthase alpha subunit; mitochondrial ATP synthetase, oligomycin-resistant; mitochondrial H+-ATP synthase alpha subunit; modifier of Min 2; Mom2; OMR; ORM; zgc:154103