Anti-Cullin 4B Antibodies

Cullin 4B Antibodies

Antibodies that detect Cullin 4B can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and Flow Cytometry. These antibodies target Cullin 4B in Human, Mouse, Rat, Canine and Zebrafish samples. Our Cullin 4B polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative Expression to confirm specificity to Cullin 4B. Find the Cullin 4B antibody that fits your needs. Choose from 1 of 31 Cullin 4B antibodies, which have been validated in experiments with 22 publications and 105 images featured in our data gallery.

Browse ... View more Antibodies that detect Cullin 4B can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and Flow Cytometry. These antibodies target Cullin 4B in Human, Mouse, Rat, Canine and Zebrafish samples. Our Cullin 4B polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative Expression to confirm specificity to Cullin 4B. Find the Cullin 4B antibody that fits your needs. Choose from 1 of 31 Cullin 4B antibodies, which have been validated in experiments with 22 publications and 105 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage. Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication. Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression. Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism. Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.

Synonyms

2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2

Cullin 4B Antibodies

Target Information

Synonyms

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