Specific Proteins Immunoassay Tests

Your partner in targeted protein analysis


What are Specific Protein assays?

Specific protein assays determine the amount or concentration of a specific protein or an array of different proteins in a sample.

Different assays in this group may aid in the characterization of a number of disorders. Individual assays in this group may aid in the characterization of:

  • Chronic heart diseases
  • Auto-immune disorders
  • Infections
  • Hemolytic diseases (anemias)
  • Metabolic disorders and other diseases
Optilite® Analyser provides automated specific protein assays
with enhanced efficiency and optimized workflow

Range of assays

The following assays are included in the Specific Protein assay range.

Cardiac assays

  • Apolipoprotein A1 and B
  • High sensitive C-reactive protein
  • Lipoprotein (a)

Inflammation assays

  • A1 Acid Glycoprotein
  • A1 Antitrypsin
  • ASO
  • CRP
  • Rheumatoid factor

Other assays

  • Caeruloplasmin
  • Haptoglobin
  • Prealbumin
  • Tetanus Toxoid**
  • Total Protein
  • Transferrin


**Automated assay unique to TBS.
Abbreviation: ASO - Antistreptolysin O; CRP – C-reactive protein 
  • Apolipoprotein A1 & B
    • Measurement of Apo A1 and B levels can aid in the assessment of cardiovascular disease and lipoprotein metabolism disorders
    • Apo A1 can aid in the assessment of risk of atherosclerotic cardiovascular disease
  • Lipoprotein (a)
    • Assessment of lipid disorders
    • Assessment of risk of atherosclerotic cardiovascular disease
    • Measurement of Lp(a), alongside LDL-cholesterol, HDL-cholesterol, apolipoprotein A-1 and apolipoprotein B, is a valuable tool in evaluation of CHD
  • High sensitive C-reactive protein (hs CRP)
    • hsCRP can aid in identification of inflammation

With regard to lipoprotein (a), the European Atherosclerosis Society recommends measurements in molar (nmol/L) scale rather than mass scale (g/L).1 As such, the Binding Site lipoprotein (a) assay measures lipoprotein (a) in nmol/L.

  • Anti-Streptolysin O (ASO)- Can be used to establish the degree of infection past or present, by β-haemolytic streptococci
  • Rheumatoid Factor (RF)- A marker that may aid in the characterisation of rheumatoid arthritis 
  • ɑ1 Acid Glycoprotein & C Reactive Protein are acute phase reactants raised in acute & chronic inflammatory conditions 
  • ɑ1 Antitrypsin deficiency may lead to conditions like pulmonary emphysema
  • High sensitive C-reactive protein (hs CRP) can aid in identification of inflammation
  • Anti-tetanus toxoid - Quantitatively measures anti-tetanus antibodies in EDTA plasma or serum
  • Haptoglobin - A diagnostic marker for hemolytic diseases such as anemia, liver disease and inflammatory conditions
  • Caeruloplasmin -  A diagnostic marker for copper metabolism disorders, such as Menkes or Wilson’s disease
  • Prealbumin - Helps in determination of nutritional status 
  • Total protein - Measurement of total proteins in blood can aid in detection of disorders such as:
    • Hypoproteinemia (which may be due to defective protein synthesized in the liver, protein loss due to impaired kidney function, intestinal malabsorption or nutritional deficiency) 
    • Hyperproteinemia (which may be due to chronic inflammatory disorders, liver cirrhosis and dehydration) 
Clinical Listing 2022/23
Clinical Listing 2022/23

View the full range of Binding Site products and services
Optilite System Brochure
Optilite System Brochure

The Optilite Analyser utilizes proven turbidimetric technology, which is known to be fast, robust and versatile, becoming the main technology for protein diagnostics worldwide
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1. Nordestgaard, B.G., Chapman, M.J., Ginsberg, H.N., The European Atherosclerosis Society Consensus Panel. (2012). Lipoprotein(a): EAS recommendations for screencing, desirable levels and management