Antibodies that detect CD50 (ICAM3) can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target CD50 (ICAM3) in Human, Canine and Mouse samples. Our CD50 (ICAM3) monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Relative expression to confirm specificity to CD50 (ICAM3). Find the CD50 (ICAM3) antibody that fits your needs. Choose from 1 of 53 CD50 (ICAM3) antibodies, which have been validated in experiments with 92 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
CD50; CDw50; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
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